Microdose Mushrooms: A Promising Treatment for Fibromyalgia?

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Microdosing mushrooms is a growing trend among people looking for alternative ways to manage chronic pain and other conditions. One area where microdosing mushrooms is gaining attention is in the treatment of fibromyalgia. Fibromyalgia is a chronic pain disorder that affects millions of people worldwide. It is characterized by widespread pain, fatigue, and other symptoms that can be debilitating and impact a person’s quality of life.

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While there is no cure for fibromyalgia, there are several treatment options available to manage symptoms. However, many people with fibromyalgia find that traditional treatments like prescription medications and physical therapy are not effective enough. This has led some to explore alternative treatments, such as microdosing mushrooms. Proponents of microdosing mushrooms for fibromyalgia claim that it can help reduce pain and other symptoms, improve mood, and increase energy levels.

What are Microdose Mushrooms

Microdose mushrooms refer to the practice of taking small amounts of psychedelic mushrooms, also known as psilocybin mushrooms, in order to achieve therapeutic benefits without experiencing the intense hallucinations associated with a full dose.

The mushrooms contain psilocybin, a psychoactive compound that can alter perception, mood, and thought. In small doses, psilocybin has been shown to have potential therapeutic effects for a variety of conditions, including depression, anxiety, addiction, and chronic pain.

While the use of microdose mushrooms for fibromyalgia is still an area of ongoing research, some individuals with the condition have reported positive effects on their symptoms, including reduced pain and improved mood. However, it is important to note that the use of psilocybin mushrooms for any medical purpose should only be done under the guidance of a qualified healthcare professional.

The Science Behind Microdosing

Microdosing mushrooms for fibromyalgia is a relatively new concept, but it has gained popularity among those who suffer from this condition. The idea behind microdosing is to consume a sub-perceptual amount of mushrooms, which means taking a small enough dose to avoid the psychoactive effects of the drug, while still receiving its therapeutic benefits.

The science behind microdosing is not yet fully understood, but there are some promising studies that suggest it may be effective for treating fibromyalgia. One study found that psilocybin, the active ingredient in mushrooms, can reduce pain and depression in patients with fibromyalgia.

Another study found that psilocybin can increase the production of brain-derived neurotrophic factor (BDNF), a protein that is important for the growth and survival of neurons. This is significant because fibromyalgia is thought to be caused by a decrease in BDNF levels.

While more research is needed to fully understand the mechanisms behind microdosing mushrooms for fibromyalgia, these early studies suggest that it may be a promising treatment option for those who suffer from this condition.

Microdosing Mushrooms for Fibromyalgia

Microdosing mushrooms is a technique that involves taking small amounts of psilocybin mushrooms for therapeutic purposes. This technique is gaining popularity as an alternative treatment for various health conditions, including fibromyalgia.

Potential Benefits

There are several potential benefits of microdosing mushrooms for fibromyalgia. Some people have reported that microdosing mushrooms has helped them manage their pain, improve their mood, and reduce their anxiety. Additionally, some people have reported that microdosing mushrooms has helped them improve their sleep quality and reduce their fatigue.

Existing Research

While there is limited research on the effects of microdosing mushrooms for fibromyalgia, some studies have suggested that psilocybin may have therapeutic potential for various health conditions. For example, a study published in the Journal of Psychopharmacology found that psilocybin may have antidepressant effects. Another study published in the Journal of Psychopharmacology found that psilocybin may be effective in reducing symptoms of anxiety and depression in cancer patients.

However, it is important to note that more research is needed to fully understand the potential benefits and risks of microdosing mushrooms for fibromyalgia. It is also important to note that psilocybin is a Schedule I controlled substance in the United States and is illegal in many other countries. Therefore, it is important to consult with a healthcare professional before considering microdosing mushrooms as a treatment option.

How to Microdose Mushrooms

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Microdosing mushrooms can be an effective way to alleviate symptoms of fibromyalgia. Here are some guidelines to follow when microdosing:

Dosage Guidelines

When microdosing mushrooms for fibromyalgia, it’s important to start with a low dose and gradually increase as needed. A good starting point is 0.1-0.2 grams of dried mushrooms, taken once every three days. If there are no adverse effects, the dosage can be increased by 0.1-0.2 grams per dose until the desired effect is achieved.

It’s important to note that the effects of microdosing mushrooms can vary from person to person, so it’s best to start with a low dose and work up slowly to find the right amount for you. Always check with your healthcare provider  prior to ingesting any medicinal contents. 

Safety Precautions

When microdosing mushrooms, it’s important to take some safety precautions to ensure a positive experience. Here are some tips to keep in mind:

  • Only use mushrooms from a trusted source.
  • Always measure your dosage carefully.
  • Avoid driving or operating heavy machinery while under the influence of mushrooms.
  • If you have a history of mental health issues, talk to your doctor before microdosing.
  • If you experience any adverse effects, stop microdosing immediately.

By following these guidelines and taking the necessary safety precautions, microdosing mushrooms can be a safe and effective way to manage fibromyalgia symptoms.


Microdosing mushrooms may provide some relief for individuals with fibromyalgia. While research is still limited, anecdotal evidence suggests that microdosing mushrooms can help alleviate pain and improve mood. However, it’s important to note that mushrooms are still a Schedule I drug in the United States and are illegal to possess or distribute.

Individuals considering microdosing mushrooms for fibromyalgia should consult with a healthcare provider and consider the potential risks and benefits. It’s also important to note that microdosing mushrooms is not a cure for fibromyalgia and should be used in conjunction with other treatments as prescribed by a healthcare provider.

Overall, more research is needed to fully understand the potential benefits and risks of microdosing mushrooms for fibromyalgia. However, for those who are interested in exploring alternative treatments, microdosing mushrooms may be worth discussing with a healthcare provider.